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K A O'Connor Selected Research

Hyperalgesia

11/2004Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats.
12/2001Systemic administration of CNI-1493, a p38 mitogen-activated protein kinase inhibitor, blocks intrathecal human immunodeficiency virus-1 gp120-induced enhanced pain states in rats.
9/2001Sciatic inflammatory neuritis (SIN): behavioral allodynia is paralleled by peri-sciatic proinflammatory cytokine and superoxide production.

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K A O'Connor Research Topics

Disease

3Pain (Aches)
11/2004 - 04/2001
3Hyperalgesia
11/2004 - 09/2001
2Infections
07/2004 - 11/2003
2Fever (Fevers)
11/2003 - 04/2001
2Shock
05/2003 - 08/2002
1Neuralgia (Stump Neuralgia)
11/2004
1Peripheral Nervous System Diseases (PNS Diseases)
11/2004
1Inflammation (Inflammations)
11/2003
1Bacterial Infections (Bacterial Infection)
11/2003
1Neuritis (Polyneuritis)
09/2001
1Edema (Dropsy)
09/2001

Drug/Important Bio-Agent (IBA)

4CytokinesIBA
11/2003 - 04/2001
2Glycoproteins (Glycoprotein)IBA
12/2001 - 04/2001
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2001 - 04/2001
2Interleukin-1beta (Interleukin 1 beta)IBA
09/2001 - 04/2001
1Neutralizing AntibodiesIBA
11/2004
1CX3C Chemokine Receptor 1IBA
11/2004
1Chemokine CX3CL1IBA
11/2004
1Anti-Bacterial Agents (Antibiotics)IBA
07/2004
1CorticosteroneIBA
11/2003
1EndotoxinsIBA
11/2003
1Dexamethasone (Maxidex)FDA LinkGeneric
05/2003
1benoxathianIBA
08/2002
1Norepinephrine (Noradrenaline)FDA LinkGeneric
08/2002
1semapimodIBA
12/2001
1Proteins (Proteins, Gene)FDA Link
12/2001
1Phosphotransferases (Kinase)IBA
12/2001
1MitogensIBA
12/2001
1p38 Mitogen-Activated Protein KinasesIBA
12/2001
1Superoxides (Superoxide)IBA
09/2001
1ZymosanIBA
09/2001
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2001
1Tumor Necrosis Factor InhibitorsIBA
04/2001
1Interleukin-1 (Interleukin 1)IBA
04/2001

Therapy/Procedure

1Spinal Injections
04/2001
1Vagotomy
04/2001